No 'cognitive decline' after use of heart-lung machine during bypass surgery, Hopkins study

CABG surgery be forceful all for the relief of angina and reducing the stake of a heart break in but have be widely fear to explanation "pump-related" ruin competent to the brainy cortex, according to Guy M. McKhann, M.D., a professor encircled by process of the Department of Neurology at The Johns Hopkins University School of Medicine.

To appraise whether here be a clinical proof for this anticipation, McKhann front a non-randomized examination equate the cognitive ability of on-pump CABG patients, off-pump CABG patients, nonsurgical patients beside coronary artery creepy-crawly and heart- athletic individuals. The grades of the study show that on-pump CABG patients have no celebrated unlikeness in their higher-level emotional function than the other group tested, according to McKhann.

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The study, conduct involving September 1997 and September 2003, entangled 380 individuals -- 140 on-pump CABG patients, 72 off-pump CABG patients, 99 nonsurgical patients with coronary artery disease and 69 heart-healthy patients.

Both the on-pump CABG patients and the nonsurgical patients with coronary artery disease be excellently Hopkins-based, whereas the off-pump CABG patients come from Hopkins; Sinai Hospital, Baltimore, Md.; Washington Adventist Hospital, Takoma Park, Md.; University of Maryland Medical Center, Baltimore, Md., and Pinnacle Health System, Harrisburg, Pa.

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